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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK9
All Species:
25.76
Human Site:
S587
Identified Species:
56.67
UniProt:
Q8TD19
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD19
NP_149107.4
979
107168
S587
H
E
V
P
Y
T
T
S
F
T
L
A
K
Q
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097546
979
107204
S587
H
E
V
P
Y
T
T
S
F
T
L
A
K
Q
L
Dog
Lupus familis
XP_547912
974
106819
S587
H
E
I
P
Y
T
T
S
F
T
L
A
K
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1R7
984
107065
S587
H
E
V
P
Y
T
T
S
F
T
L
A
K
Q
L
Rat
Rattus norvegicus
NP_001100217
958
104862
S586
H
E
V
P
Y
T
T
S
F
T
L
A
K
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506669
536
57599
F181
E
R
G
R
L
L
T
F
G
S
N
K
C
G
Q
Chicken
Gallus gallus
XP_001235085
1086
118657
S699
C
E
V
P
Y
A
T
S
L
T
L
A
K
Q
L
Frog
Xenopus laevis
Q7ZZC8
944
104521
S569
Q
E
V
P
Y
T
T
S
L
T
L
A
K
Q
L
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
V342
L
P
M
L
N
T
E
V
I
Q
V
S
L
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781356
721
79856
I366
S
V
T
V
E
K
E
I
F
T
W
A
N
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXT4
555
62879
K200
M
Y
E
M
A
A
H
K
P
P
F
K
A
S
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.4
95.7
N.A.
95
93.6
N.A.
44.8
76
69.5
24.1
N.A.
N.A.
N.A.
N.A.
40.2
Protein Similarity:
100
N.A.
99.4
96.8
N.A.
96.4
95
N.A.
48.9
81.4
80.1
41
N.A.
N.A.
N.A.
N.A.
52.8
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
6.6
80
86.6
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
80
86.6
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
19
0
0
0
0
0
73
10
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
10
64
10
0
10
0
19
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
55
0
10
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
10
0
0
0
0
19
0
% G
% His:
46
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
10
0
0
0
19
64
0
0
% K
% Leu:
10
0
0
10
10
10
0
0
19
0
64
0
10
0
64
% L
% Met:
10
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
10
0
10
0
0
% N
% Pro:
0
10
0
64
0
0
0
0
10
10
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
10
0
0
0
64
10
% Q
% Arg:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
10
0
0
0
0
0
0
64
0
10
0
10
0
10
0
% S
% Thr:
0
0
10
0
0
64
73
0
0
73
0
0
0
0
0
% T
% Val:
0
10
55
10
0
0
0
10
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
10
0
0
64
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _